Site-specifically arraying small molecules or proteins on DNA using an expanded genetic alphabet

We have developed a class of replicable unnatural DNA base pairs formed between d5SICS and either dMMO2, dDMO, or dNaM. To explore the use of these pairs to produce site-specifically labeled DNA, we report the synthesis of a variety of derivatives bearing propynyl groups, an analysis of their polyme...

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Autors principals: Li, Zhengtao, Lavergne, Thomas, Malyshev, Denis A., Zimmermann, Jörg, Adhikary, Ramkrishna, Dhami, Kirandeep, Ordoukhanian, Phillip, Sun, Zhelin, Xiang, Jie, Romesberg, Floyd E.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983968/
https://ncbi.nlm.nih.gov/pubmed/24026962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201302496
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