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Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline

The viability of any species requires that the genome is kept stable as it is transmitted from generation to generation by the germ cells. One of the challenges to transgenerational genome stability is the potential mutagenic activity of transposable genetic elements, particularly retrotransposons....

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Détails bibliographiques
Auteurs principaux: Crichton, James H., Dunican, Donncha S., MacLennan, Marie, Meehan, Richard R., Adams, Ian R.
Format: Artigo
Langue:Inglês
Publié: Springer Basel 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983883/
https://ncbi.nlm.nih.gov/pubmed/24045705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1468-0
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