Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes

Meiosis relies on the SPO11 endonuclease to generate the recombinogenic DNA double strand breaks (DSBs) required for homologous chromosome synapsis and segregation. The number of meiotic DSBs needs to be sufficient to allow chromosomes to search for and find their homologs, but not excessive to the...

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Publicat a:PLoS Genet
Autors principals: Crichton, James H., Playfoot, Christopher J., MacLennan, Marie, Read, David, Cooke, Howard J., Adams, Ian R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533463/
https://ncbi.nlm.nih.gov/pubmed/28708824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006904
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