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The control of Spo11's interaction with meiotic recombination hotspots

Programmed double-strand breaks (DSBs), which initiate meiotic recombination, arise through the activity of the evolutionary conserved topoisomerase homolog Spo11. Spo11 is believed to catalyze the DNA cleavage reaction in the initial step of DSB formation, while at least a further 11 factors assist...

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Hlavní autoři: Prieler, Silvia, Penkner, Alexandra, Borde, Valérie, Klein, Franz
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC545890/
https://ncbi.nlm.nih.gov/pubmed/15655113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.321105
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