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The control of Spo11's interaction with meiotic recombination hotspots

Programmed double-strand breaks (DSBs), which initiate meiotic recombination, arise through the activity of the evolutionary conserved topoisomerase homolog Spo11. Spo11 is believed to catalyze the DNA cleavage reaction in the initial step of DSB formation, while at least a further 11 factors assist...

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Detalhes bibliográficos
Main Authors: Prieler, Silvia, Penkner, Alexandra, Borde, Valérie, Klein, Franz
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC545890/
https://ncbi.nlm.nih.gov/pubmed/15655113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.321105
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