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Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline

The viability of any species requires that the genome is kept stable as it is transmitted from generation to generation by the germ cells. One of the challenges to transgenerational genome stability is the potential mutagenic activity of transposable genetic elements, particularly retrotransposons....

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Detalhes bibliográficos
Main Authors: Crichton, James H., Dunican, Donncha S., MacLennan, Marie, Meehan, Richard R., Adams, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983883/
https://ncbi.nlm.nih.gov/pubmed/24045705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1468-0
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