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Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline
Mouse primordial germ cells (PGCs) erase global DNA methylation (5mC) as part of the comprehensive epigenetic reprogramming that occurs during PGC development. 5mC plays an important role in maintaining stable gene silencing and repression of transposable elements (TE) but it is not clear how the ex...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Company of Biologists
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436114/ https://ncbi.nlm.nih.gov/pubmed/22949617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.081661 |
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