The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways

We demonstrate that a direct interaction between the methyl-CpG-dependent transcription repressor Kaiso and xTcf3, a transducer of the Wnt signalling pathway, results in their mutual disengagement from their respective DNA-binding sites. Thus, the transcription functions of xTcf3 can be inhibited by...

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Autori principali: Ruzov, Alexey, Hackett, Jamie A., Prokhortchouk, Anna, Reddington, James P., Madej, Monika J., Dunican, Donncha S., Prokhortchouk, Egor, Pennings, Sari, Meehan, Richard R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2009
Soggetti:
Research Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685940/
https://ncbi.nlm.nih.gov/pubmed/19158184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.025577
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