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Reconciling views on T cell receptor germline bias for MHC
Whether MHC restriction by the T cell receptor (TCR) is a product of evolutionary pressures leading to germline-encoded ‘rules of engagement’ remains avidly debated. Structural results derived from analysis of TCR–peptide–MHC complexes appear to support a model of physical specificity between TCR ge...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983780/ https://ncbi.nlm.nih.gov/pubmed/22771140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.05.005 |
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