Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness

Fludarabine refractoriness (FR) represents an unsolved clinical problem of chronic lymphocytic leukemia (CLL) management. Although next-generation sequencing studies have led to the identification of a number of genes frequently mutated in FR-CLL, a comprehensive evaluation of the FR-CLL genome has...

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Détails bibliographiques
Auteurs principaux: Messina, Monica, Del Giudice, Ilaria, Khiabanian, Hossein, Rossi, Davide, Chiaretti, Sabina, Rasi, Silvia, Spina, Valeria, Holmes, Antony B., Marinelli, Marilisa, Fabbri, Giulia, Piciocchi, Alfonso, Mauro, Francesca R., Guarini, Anna, Gaidano, Gianluca, Dalla-Favera, Riccardo, Pasqualucci, Laura, Rabadan, Raul, Foà, Robin
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2014
Sujets:
Lymphoid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983613/
https://ncbi.nlm.nih.gov/pubmed/24550227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-534271
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