Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome

Richter syndrome (RS) derives from the rare transformation of chronic lymphocytic leukemia (CLL) into an aggressive lymphoma, most commonly of the diffuse large B cell lymphoma (DLBCL) type. The molecular pathogenesis of RS is only partially understood. By combining whole-exome sequencing and copy-n...

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Main Authors: Fabbri, Giulia, Khiabanian, Hossein, Holmes, Antony B., Wang, Jiguang, Messina, Monica, Mullighan, Charles G., Pasqualucci, Laura, Rabadan, Raul, Dalla-Favera, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804949/
https://ncbi.nlm.nih.gov/pubmed/24127483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131448
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