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Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis
Histone acetylation plays critical roles in chromatin remodeling, DNA repair, and epigenetic regulation of gene expression, but the underlying mechanisms are unclear. Proteasomes usually catalyze ATP- and polyubiquitin-dependent proteolysis. Here we show that the proteasomes containing the activator...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983474/ https://ncbi.nlm.nih.gov/pubmed/23706739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.032 |
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