Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis

Histone acetylation plays critical roles in chromatin remodeling, DNA repair, and epigenetic regulation of gene expression, but the underlying mechanisms are unclear. Proteasomes usually catalyze ATP- and polyubiquitin-dependent proteolysis. Here we show that the proteasomes containing the activator...

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Main Authors: Qian, Min-Xian, Pang, Ye, Liu, Cui Hua, Haratake, Kousuke, Du, Bo-Yu, Ji, Dan-Yang, Wang, Guang-Fei, Zhu, Qian-Qian, Song, Wei, Yu, Yadong, Zhang, Xiao-Xu, Huang, Hai-Tao, Miao, Shiying, Chen, Lian-Bin, Zhang, Zi-Hui, Liang, Ya-Nan, Liu, Shan, Cha, Hwangho, Yang, Dong, Zhai, Yonggong, Komatsu, Takuo, Tsuruta, Fuminori, Li, Haitao, Cao, Cheng, Li, Wei, Li, Guo-Hong, Cheng, Yifan, Chiba, Tomoki, Wang, Linfang, Goldberg, Alfred L., Shen, Yan, Qiu, Xiao-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983474/
https://ncbi.nlm.nih.gov/pubmed/23706739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.032
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