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Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility

Protein degradation mediated by the proteasome is important for the protein homeostasis. Various proteasome activators, such as PA28 and PA200, regulate the proteasome function. Here we show double knockout (dKO) mice of Psme3 and Psme4 (genes for PA28γ and PA200), but not each single knockout mice,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Lin, Haratake, Kousuke, Miyahara, Hatsumi, Chiba, Tomoki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802386/
https://ncbi.nlm.nih.gov/pubmed/27003159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23171
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