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A Simple Litmus Test for Aldehyde Oxidase Metabolism of Heteroarenes
[Image: see text] The bioavailability of aromatic azaheterocyclic drugs can be affected by the activity of aldehyde oxidase (AO). Susceptibility to AO metabolism is difficult to predict computationally and can be complicated in vivo by differences between species. Here we report the use of bis(((dif...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3983350/ https://ncbi.nlm.nih.gov/pubmed/24472070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4017976 |
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