C–H Methylation of Heteroarenes Inspired by Radical SAM Methyl Transferase

[Image: see text] A practical C–H functionalization method for the methylation of heteroarenes is presented. Inspiration from Nature’s methylating agent, S-adenosylmethionine (SAM), allowed for the design and development of zinc bis(phenylsulfonylmethanesulfinate), or PSMS. The action of PSMS on a h...

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Detalhes bibliográficos
Main Authors: Gui, Jinghan, Zhou, Qianghui, Pan, Chung-Mao, Yabe, Yuki, Burns, Aaron C., Collins, Michael R., Ornelas, Martha A., Ishihara, Yoshihiro, Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988686/
https://ncbi.nlm.nih.gov/pubmed/24611732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5007838
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