Dynamic Behavior of the Active and Inactive States of the Adenosine A(2A) Receptor

[Image: see text] The adenosine A(2A) receptor (A(2A)R) belongs to the superfamily of membrane proteins called the G-protein-coupled receptors (GPCRs) that form one of the largest superfamilies of drug targets. Deriving thermostable mutants has been one of the strategies used for crystallization of...

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Bibliographic Details
Main Authors: Lee, Sangbae, Bhattacharya, Supriyo, Grisshammer, Reinhard, Tate, Christopher, Vaidehi, Nagarajan
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983344/
https://ncbi.nlm.nih.gov/pubmed/24579769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp411618h
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