Cytosolic Peroxidases Protect the Lysosome of Bloodstream African Trypanosomes from Iron-Mediated Membrane Damage

African trypanosomes express three virtually identical non-selenium glutathione peroxidase (Px)-type enzymes which preferably detoxify lipid-derived hydroperoxides. As shown previously, bloodstream Trypanosoma brucei lacking the mitochondrial Px III display only a weak and transient proliferation de...

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Detalhes bibliográficos
Main Authors: Hiller, Corinna, Nissen, Amrei, Benítez, Diego, Comini, Marcelo A., Krauth-Siegel, R. Luise
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983053/
https://ncbi.nlm.nih.gov/pubmed/24722489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004075
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