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The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17
Membrane fusion is generally controlled by Rabs, soluble N-ethylmaleimide–sensitive factor attachment protein receptors (SNAREs), and tethering complexes. Syntaxin 17 (STX17) was recently identified as the autophagosomal SNARE required for autophagosome–lysosome fusion in mammals and Drosophila. In...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982997/ https://ncbi.nlm.nih.gov/pubmed/24554770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-08-0447 |
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