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Application of a High-Resolution Mass-Spectrometry-Based DNA Adductomics Approach for Identification of DNA Adducts in Complex Mixtures

[Image: see text] Liquid chromatography coupled with mass spectrometry (LC-MS) is the method of choice for analysis of covalent modification of DNA. DNA adductomics is an extension of this approach allowing for the screening for both known and unknown DNA adducts. In the research reported here, a ne...

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Detalhes bibliográficos
Main Authors: Balbo, Silvia, Hecht, Stephen S., Upadhyaya, Pramod, Villalta, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982966/
https://ncbi.nlm.nih.gov/pubmed/24410521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac403565m
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