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Targeted High Resolution LC/MS(3) Adductomics Method for the Characterization of Endogenous DNA Damage

DNA can be damaged through covalent modifications of the nucleobases by endogenous processes. These modifications, commonly referred to as DNA adducts, can persist and may lead to mutations, and ultimately to the initiation of cancer. A screening methodology for the majority of known endogenous DNA...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Carrà, Andrea, Guidolin, Valeria, Dator, Romel P., Upadhyaya, Pramod, Kassie, Fekadu, Villalta, Peter W., Balbo, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822301/
https://ncbi.nlm.nih.gov/pubmed/31709223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00658
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