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Analysis of a Malondialdehyde–Deoxyguanosine Adduct in Human Leukocyte DNA by Liquid Chromatography Nanoelectrospray–High-Resolution Tandem Mass Spectrometry

[Image: see text] Malondialdehyde (MDA), an endogenous genotoxic product formed upon lipid peroxidation and prostaglandin biosynthesis, can react with DNA to form stable adducts. These adducts may contribute to the development of such inflammation-mediated diseases as cancer and cardiovascular and n...

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Main Authors: Ma, Bin, Villalta, Peter W., Balbo, Silvia, Stepanov, Irina
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203394/
https://ncbi.nlm.nih.gov/pubmed/25181548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx5002699
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