Heterogeneity of Abnormal Prion Protein (PrP(Sc)) in Murine Scrapie Prions Determined by PrP(Sc)-Specific Monoclonal Antibodies

In prion diseases, abnormal prion protein (PrP(Sc)) is considered as the main component of the infectious agent. Delineation of PrP(Sc) conformation is expected to be a critical factor in understanding properties of prions. However, practical methods to differentiate between conformers of PrP(Sc) ar...

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Bibliographic Details
Main Authors: USHIKI-KAKU, Yuko, SHIMIZU, Yoshihisa, TABETA, Naoko, IWAMARU, Yoshifumi, OGAWA-GOTO, Kiyoko, HATTORI, Shunji, YOKOYAMA, Takashi
Format: Artigo
Language:Inglês
Published: The Japanese Society of Veterinary Science 2013
Subjects:
Virology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982826/
https://ncbi.nlm.nih.gov/pubmed/24132297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.13-0409
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