Large electrostatic differences in the binding thermodynamics of a cationic peptide to oligomeric and polymeric DNA.
Results presented here demonstrate that the thermodynamics of oligocation binding to polymeric and oligomeric DNA are not equivalent because of long-range electrostatic effects. At physiological cation concentrations (0.1-0.3 M) the binding of an oligolysine octacation KWK6-NH2 (+8 charge) to single...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1996
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39828/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8637905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.6.2511 |
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