Large electrostatic differences in the binding thermodynamics of a cationic peptide to oligomeric and polymeric DNA.
Results presented here demonstrate that the thermodynamics of oligocation binding to polymeric and oligomeric DNA are not equivalent because of long-range electrostatic effects. At physiological cation concentrations (0.1-0.3 M) the binding of an oligolysine octacation KWK6-NH2 (+8 charge) to single...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1996
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39828/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8637905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.6.2511 |
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