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Lanthanide-binding helix-turn-helix peptides: Solution structure of a designed metallonuclease

A designed lanthanide-binding chimeric peptide based on the strikingly similar geometries of the EF-hand and helix-turn-helix (HTH) motifs was investigated by NMR and CD spectroscopy and found to retain the same overall solution structure of the parental motifs. CD spectroscopy showed that the 33-me...

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Bibliografiske detaljer
Main Authors: Welch, Joel T., Kearney, William R., Franklin, Sonya J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152989/
https://ncbi.nlm.nih.gov/pubmed/12644701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0536562100
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