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Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments.

Expression of the human alpha and beta globin gene clusters is regulated by remote sequences, referred to as HS -40 and the beta-locus control region (beta-LCR) that lie 5-40 kb upstream of the genes they activate. Because of their common ancestry, similar organization and coordinate expression it h...

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Detaylı Bibliyografya
Asıl Yazarlar: Craddock, C F, Vyas, P, Sharpe, J A, Ayyub, H, Wood, W G, Higgs, D R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC398265/
https://ncbi.nlm.nih.gov/pubmed/7737123
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