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Analysis of a 70 kb segment of DNA containing the human zeta and alpha-globin genes linked to their regulatory element (HS-40) in transgenic mice.

We have ligated two cosmids through an oligonucleotide linker to produce a single fragment spanning 70 kb of the human alpha-globin cluster, in which the alpha-like globin genes (zeta 2, alpha 2 and alpha 1), their regulatory element (HS-40) and erythroid-specific DNase I hypersensitive sites accura...

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Dettagli Bibliografici
Autori principali: Gourdon, G, Sharpe, J A, Wells, D, Wood, W G, Higgs, D R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC331901/
https://ncbi.nlm.nih.gov/pubmed/7937139
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