Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis.
Engineering site-specific amino acid substitutions into the protein-tyrosine phosphatase (PTPase) PTP1 and the dual-specific vaccinia H1-related phosphatase (VHR), has kinetically isolated the two chemical steps of the reaction and provided a rare opportunity for examining transition states and dire...
Guardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
|---|---|
| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1996
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8637902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.6.2493 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|