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Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate.

Alendronate (ALN), an aminobisphosphonate used in the treatment of osteoporosis, is a potent inhibitor of bone resorption. Its molecular target is still unknown. This study examines the effects of ALN on the activity of osteoclast protein-tyrosine phosphatase (PTP; protein-tyrosine-phosphate phospho...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Schmidt, A, Rutledge, S J, Endo, N, Opas, E E, Tanaka, H, Wesolowski, G, Leu, C T, Huang, Z, Ramachandaran, C, Rodan, S B, Rodan, G A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8610169/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.7.3068
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