Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate.
Alendronate (ALN), an aminobisphosphonate used in the treatment of osteoporosis, is a potent inhibitor of bone resorption. Its molecular target is still unknown. This study examines the effects of ALN on the activity of osteoclast protein-tyrosine phosphatase (PTP; protein-tyrosine-phosphate phospho...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1996
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8610169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.7.3068 |
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