Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate.

Alendronate (ALN), an aminobisphosphonate used in the treatment of osteoporosis, is a potent inhibitor of bone resorption. Its molecular target is still unknown. This study examines the effects of ALN on the activity of osteoclast protein-tyrosine phosphatase (PTP; protein-tyrosine-phosphate phospho...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Schmidt, A, Rutledge, S J, Endo, N, Opas, E E, Tanaka, H, Wesolowski, G, Leu, C T, Huang, Z, Ramachandaran, C, Rodan, S B, Rodan, G A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8610169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.7.3068
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