Pre‐clinical efficacy of PU‐H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma

Ewing sarcoma is characterized by multiple deregulated pathways that mediate cell survival and proliferation. Heat shock protein 90 (HSP90) is a critical component of the multi‐chaperone complexes that regulate the disposition and activity of a large number of proteins involved in cell‐signaling sys...

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Sonraí Bibleagrafaíochta
Main Authors: Ambati, Srikanth R., Lopes, Eloisi Caldas, Kosugi, Kohji, Mony, Ullas, Zehir, Ahmet, Shah, Smit K., Taldone, Tony, Moreira, Andre L., Meyers, Paul A., Chiosis, Gabriela, Moore, Malcolm A.S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2013
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982393/
https://ncbi.nlm.nih.gov/pubmed/24388362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.12.005
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