PET imaging of ischemia-induced impairment of mitochondrial complex I function in monkey brain

To assess the capability of (18)F-2-tert-butyl-4-chloro-5-{6-[2-(2-fluoroethoxy)-ethoxy]-pyridin-3-ylmethoxy}-2H-pyridazin-3-one ((18)F-BCPP-EF), a novel positron emission tomography (PET) probe for mitochondrial complex I (MC-I) activity, as a specific marker of ischemia-induced neuronal death with...

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Hlavní autoři: Tsukada, Hideo, Ohba, Hiroyuki, Nishiyama, Shingo, Kanazawa, Masakatsu, Kakiuchi, Takeharu, Harada, Norihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982099/
https://ncbi.nlm.nih.gov/pubmed/24447952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.5
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