Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis

A candidate vaccine to prevent human schistosomiasis is under development. The vaccine is comprised of a recombinant 9 kDa antigen protein corresponding to the large extracellular domain of a tetraspanin surface antigen protein of Schistosoma mansoni, Sm-TSP-2. Here, we describe the biophysical prof...

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Autores principales: Cheng, Weiqiang, Curti, Elena, Rezende, Wanderson C, Kwityn, Clifford, Zhan, Bin, Gillespie, Portia, Plieskatt, Jordan, Joshi, Sangeeta B., Volkin, David B., Hotez, Peter J, Middaugh, C Russell, Bottazzi, Maria Elena
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
Materias:
Short Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981844/
https://ncbi.nlm.nih.gov/pubmed/23880663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25788
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