Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: A vaccine candidate for human intestinal schistosomiasis

A novel recombinant protein vaccine for human schistosomiasis caused by Schistosoma mansoni is under development. The Sm-TSP-2 schistosomiasis vaccine is comprised of a 9 kDa recombinant protein corresponding to the extracellular domain of a unique S. mansoni tetraspanin. Here, we describe the cloni...

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Detalhes bibliográficos
Main Authors: Curti, Elena, Kwityn, Clifford, Zhan, Bin, Gillespie, Portia, Brelsford, Jill, Deumic, Vehid, Plieskatt, Jordan, Rezende, Wanderson C, Tsao, Eric, Kalampanayil, Bose, Hotez, Peter J, Bottazzi, Maria Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981843/
https://ncbi.nlm.nih.gov/pubmed/23899507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25787
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