SERCA mutant E309Q binds two Ca(2+) ions but adopts a catalytically incompetent conformation

The sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) couples ATP hydrolysis to transport of Ca(2+). This directed energy transfer requires cross-talk between the two Ca(2+) sites and the phosphorylation site over 50 Å distance. We have addressed the mechano-structural basis for this intramolecular...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Clausen, Johannes D, Bublitz, Maike, Arnou, Bertrand, Montigny, Cédric, Jaxel, Christine, Møller, Jesper Vuust, Nissen, Poul, Andersen, Jens Peter, le Maire, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981149/
https://ncbi.nlm.nih.gov/pubmed/24270570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.250
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados