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The SERCA residue Glu340 mediates interdomain communication that guides Ca(2+) transport

The sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) is a P-type ATPase that transports Ca(2+) from the cytosol into the sarco(endo)plasmic reticulum (SR/ER) lumen, driven by ATP. This primary transport activity depends on tight coupling between movements of the transmembrane helices forming the t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Geurts, Maxwell M. G., Clausen, Johannes D., Arnou, Bertrand, Montigny, Cédric, Lenoir, Guillaume, Corey, Robin A., Jaxel, Christine, Møller, Jesper V., Nissen, Poul, Andersen, Jens Peter, le Maire, Marc, Bublitz, Maike
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733806/
https://ncbi.nlm.nih.gov/pubmed/33229570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014896117
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