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Peripherally administrated prions reach the brain at sub-infectious quantities in experimental hamsters

The mechanisms implicated in prion infection and tissue distribution are not completely understood. In this study we investigated the levels of 263K prions in brain and spleen of Syrian hamsters few days after intra-peritoneal challenge. For this purpose we utilized the PMCA technology which permits...

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Detalhes bibliográficos
Main Authors: Chen, Baian, Soto, Claudio, Morales, Rodrigo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980850/
https://ncbi.nlm.nih.gov/pubmed/24492001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.01.038
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