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Estimating prion concentration in fluids and tissues by quantitative PMCA
Prions, the proteinaceous infectious agent responsible for prion diseases, can be detected with high sensitivity by protein misfolding cyclic amplification (PMCA) technology. Here we describe a quantitative PMCA procedure to calculate the concentration of very low levels of prions in biological samp...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4049222/ https://ncbi.nlm.nih.gov/pubmed/20512142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1465 |
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