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Progesterone Antagonist Therapy in a Pelizaeus-Merzbacher Mouse Model

Pelizaeus-Merzbacher disease (PMD) is a severe hypomyelinating disease, characterized by ataxia, intellectual disability, epilepsy, and premature death. In the majority of cases, PMD is caused by duplication of PLP1 that is expressed in myelinating oligodendrocytes. Despite detailed knowledge of PLP...

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Bibliografische gegevens
Hoofdauteurs: Prukop, Thomas, Epplen, Dirk B., Nientiedt, Tobias, Wichert, Sven P., Fledrich, Robert, Stassart, Ruth M., Rossner, Moritz J., Edgar, Julia M., Werner, Hauke B., Nave, Klaus-Armin, Sereda, Michael W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980417/
https://ncbi.nlm.nih.gov/pubmed/24680886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.03.001
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