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Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease
OBJECTIVE: Pelizaeus–Merzbacher disease (PMD) is a progressive and lethal leukodystrophy caused by mutations affecting the proteolipid protein (PLP1) gene. The most common cause of PMD is a duplication of PLP1 and at present there is no curative therapy available. METHODS: By using transgenic mice c...
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| Publicat a: | Ann Clin Transl Neurol |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4554440/ https://ncbi.nlm.nih.gov/pubmed/26339673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.219 |
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