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Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease
OBJECTIVE: Pelizaeus–Merzbacher disease (PMD) is a progressive and lethal leukodystrophy caused by mutations affecting the proteolipid protein (PLP1) gene. The most common cause of PMD is a duplication of PLP1 and at present there is no curative therapy available. METHODS: By using transgenic mice c...
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Publicado no: | Ann Clin Transl Neurol |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley & Sons, Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4554440/ https://ncbi.nlm.nih.gov/pubmed/26339673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.219 |
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