Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease

OBJECTIVE: Pelizaeus–Merzbacher disease (PMD) is a progressive and lethal leukodystrophy caused by mutations affecting the proteolipid protein (PLP1) gene. The most common cause of PMD is a duplication of PLP1 and at present there is no curative therapy available. METHODS: By using transgenic mice c...

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Bibliografske podrobnosti
izdano v:Ann Clin Transl Neurol
Main Authors: Epplen, Dirk B, Prukop, Thomas, Nientiedt, Tobias, Albrecht, Philipp, Arlt, Friederike A, Stassart, Ruth M, Kassmann, Celia M, Methner, Axel, Nave, Klaus-Armin, Werner, Hauke B, Sereda, Michael W
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554440/
https://ncbi.nlm.nih.gov/pubmed/26339673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.219
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