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Extension of the Germinal Center Stage of B-cell Development Promotes Autoantibodies in BXD2 Mice
OBJECTIVE: Regulator of G-protein Signaling (RGS) proteins inhibit chemokine signaling by desensitizing G-protein coupled receptor signals. The mechanisms by which RGS13 promotes the generation of pathogenic autoantibodies in germinal centers (GC) were determined using BXD2-Rgs13(−/−) mice. METHODS:...
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| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979745/ https://ncbi.nlm.nih.gov/pubmed/23818250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38059 |
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