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IL-17RA is Essential for Optimal Localization of Follicular T Helper Cells in the Germinal Center Light Zone to Promote Autoantibody-Producing B cells

Germinal centers provide a microenvironment that promotes and regulates the interactions of B-cells with follicular T-helper cells (T(FH)). Here we show that there are significantly higher frequencies of CXCR5(+)ICOS(+)T(FH) cells in autoimmune BXD2 mice, and these cells express both interleukin (IL...

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Detalhes bibliográficos
Main Authors: Ding, Yanna, Li, Jun, Wu, Qi, Yang, Pingar, Luo, Bao, Xie, Shutao, Druey, Kirk M., Zajac, Allan J., Hsu, Hui-Chen, Mountz, John D
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819396/
https://ncbi.nlm.nih.gov/pubmed/23858031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300479
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