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IL-17 Activates the Canonical NF-κB Signaling Pathway In Autoimmune B Cells of BXD2 Mice to Upregulate the Expression of Regulators of G-Protein Signaling 16

We previously identified that autoreactive B cells from BXD2 mice can be targeted by IL-17, leading to upregulation of the expression of regulators of G-protein signaling (Rgs) genes that facilitated the development of spontaneous germinal centers. Little is known about the signaling pathway used by...

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Библиографические подробности
Главные авторы: Xie, Shutao, Li, Jun, Wang, John H., Wu, Qi, Yang, PingAr, Hsu, Hui-Chen, Smythies, Lesley E., Mountz, John D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849003/
https://ncbi.nlm.nih.gov/pubmed/20139273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903133
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