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Defective Follicular Exclusion of Apoptotic Antigens Due to Marginal Zone Macrophage Defects in Autoimmune BXD2 Mice

Marginal zone macrophages (MZMs) act as a barrier to entry of circulating apoptotic debris into the follicles of secondary lymphoid organs. In autoimmune BXD2 mice, there is a progressive reduction in the function and numbers of MZMs. Absence of MZMs results in retention of apoptotic cell debris wit...

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Detalhes bibliográficos
Main Authors: Li, Hao, Wu, Qi, Li, Jun, Yang, PingAr, Zhu, Zilu, Luo, Bao, Hsu, Hui-Chen, Mountz, John D
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656168/
https://ncbi.nlm.nih.gov/pubmed/23543760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300041
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