Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase

TPL-2 expression is required for efficient polarization of naïve T cells to Th1 effector cells in vitro, and for Th1-mediated immune responses. In the present study, we investigated the potential role of TPL-2 in Th17 cells. TPL-2 was found to be dispensable for Th17 cell differentiation in vitro, a...

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Huvudupphovsmän: Sriskantharajah, Srividya, Gückel, Eva, Tsakiri, Niki, Kierdorf, Katrin, Brender, Christine, Ben-Addi, Abduelhakem, Veldhoen, Marc, Tsichlis, Philip N., Stockinger, Brigitta, O’Garra, Anne, Prinz, Marco, Kollias, George, Ley, Steven C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979668/
https://ncbi.nlm.nih.gov/pubmed/24639351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300172
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