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Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

Th17 cell differentiation is dependent on interleukin (IL)-6 and transforming growth factor (TGF)-β, and it is modulated by activation of the aryl hydrocarbon receptor (AhR). In this study, we show that differentiation of Th17 cells, but not Th1 or induced regulatory T (iT reg) cells, is increased b...

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Hlavní autoři: Veldhoen, Marc, Hirota, Keiji, Christensen, Jillian, O'Garra, Anne, Stockinger, Brigitta
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626686/
https://ncbi.nlm.nih.gov/pubmed/19114668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081438
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