Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions

Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other autoimmune diseases, but the mechanisms are largely unknown. Here we show that the aryl hydrocarbon receptor (AhR), a transcription factor that senses environmental stimuli, modulates pathology in psoriasis. Ah...

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Detalhes bibliográficos
Main Authors: Di Meglio, Paola, Duarte, João H., Ahlfors, Helena, Owens, Nick D.L., Li, Ying, Villanova, Federica, Tosi, Isabella, Hirota, Keiji, Nestle, Frank O., Mrowietz, Ulrich, Gilchrist, Michael J., Stockinger, Brigitta
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067745/
https://ncbi.nlm.nih.gov/pubmed/24909886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.04.019
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