Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions

Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other autoimmune diseases, but the mechanisms are largely unknown. Here we show that the aryl hydrocarbon receptor (AhR), a transcription factor that senses environmental stimuli, modulates pathology in psoriasis. Ah...

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Autors principals: Di Meglio, Paola, Duarte, João H., Ahlfors, Helena, Owens, Nick D.L., Li, Ying, Villanova, Federica, Tosi, Isabella, Hirota, Keiji, Nestle, Frank O., Mrowietz, Ulrich, Gilchrist, Michael J., Stockinger, Brigitta
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067745/
https://ncbi.nlm.nih.gov/pubmed/24909886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.04.019
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